Direct measurement of serum iron and binding capacity.

Effects of Alpha-Lipoid Acid on Serum Iron, Total Iron Binding Capacity and Hematological Indices in β-Thalassemia Major Patients: A Cross Over Clinical Trial

Background and Objectives: Accumulation of iron is the most common consequences of repeated blood transfusions in β-thalassemia major patients. Iron chelating effects of alpha-lipoic acid have been reported by several studies. The aim of this study was to investigate effects of supplementation with alpha-lipoic acid, as a chelator, on serum iron and hematological indices in these patients.  Ma...

Investigating Changes in the Serum Iron, TIBC (Total Iron Binding Capacity) and Transferrin Levels in Patients with Morbid Obesity Undergoing Bariatric Surgery in Kerman in 2018: A Short Report

Background and Objectives: Bariatric surgery is one of the most effective treatments for obesity. This study was designed to investigate changes in the serum iron, TIBC (Total Iron Binding Capacity) and transferrin levels in patients with morbid obesity undergoing bariatric surgery in Kerman in 2018. Materials and Methods: This prospective study was carried out on 65 participants who had gone ...

Influence of iron saturation as a possible source of error in the immunoturbidimetric determination of serum transferrin.

The serum transferrin concentration is usually overestimated when assessed as total iron binding capacity, because iron binds not only to transferrin but also, non-specifically, to other serum proteins [l-3]. Transferrin concentration can be measured directly by immunochemical methods including: radial immunodiffusion [ 1,2,4-61, immunonephelometric assay [6,7] and immunoturbidimetric assay [8,...

Association between helicobacter pylori infection and serum iron profile

Background: It is clear that Helicobacter pylori (H. pylori) is a spiral bacterium that infects human and causes gastritis and peptic ulcer. The aim of this study was to determine the relationship between H .pylori infection and the iron status of the body. Methods: This study was conducted in Shahid Beheshti Hospital of Babol University of Medical Sciences, Babol, Iran from August 2007 to July...

Indicators of the iron status of populations: free erythrocyte protoporphyrin and zinc protoporphyrin; serum and plasma iron, total iron binding capacity and transferrin saturation; and serum transferrin receptor

Direct determination and binding capacity of serum iron.

A modified direct procedure is described for measuring serum iron (SI) levels and serum unsaturated iron-binding capacities (UIBC). Protein digestion or precipitation, as well as extraction of the color of the iron complex are eliminated. The protein-bound iron is dissociatedat acid pH, reacted with terpyridine in the ferrous state, and the optical density is read at 552 m. The UIBC is measured...